Heart Failure Journal Club Schedule
(2006-2007)

Second Thursdays, 11:00 am – 12:30 pm
Room 116, SMI
Timothy J. Kamp, MD, Ph.D., Associate Professor, Medicine (CV), Chair
Contact info@cvrc.wisc.edu for further information

Fall 2006

Sep. 14, 2006
Timothy J. Kamp, MD, Ph.D. Associate Professor, Medicine (Cardiovascular)

Diabetes Promotes Cardiac Stem Cell Aging and Heart Failure, Which Are Prevented by Deletion of the p66shc Gene, Marcello Rota, Nicole LeCapitaine, Toru Hosoda, Alessandro Boni, Antonella De Angelis, Maria Elena Padin-Iruegas, Grazia Esposito, Serena Vitale, Konrad Urbanek, Claudia Casarsa, Marco Giorgio, Thomas F. Luscher, Pier Giuseppe Pelicci, Piero Anversa, Annarosa Leri, Jan Kajstura (Circ Res. 2006;99:42-52.)

Oct. 19, 2006 (note: different week)
Harold D. Schultz, Ph.D. Professor, Cellular and Integrative Physiology, University of Nebraska Medical Center

Enhanced chemoreflex control of sympathetic outflow in heart failure

Discussion Articles: Enhanced sensitivity of Kv channels to hypoxia in the rabbit carotid body in heart failure: role of angiotensin II. Li YL, Schultz HD. J Physiol. 2006 Aug 15; 575(Pt 1):215-27. Epub 2006 Jun 15.

Angiotensin II enhances carotid body chemoreflex control of sympathetic outflow in chronic heart failure rabbits. Li YL, Xia XH, Zheng H, Gao L, Li YF, Liu D, Patel KP, Wang W, Schultz HD. Cardiovasc Res. 2006 Jul 1;71(1):129-38. Epub 2006 Mar 24.

Nov. 9, 2006
Stacey Brickson, Ph.D., Postdoctoral Trainee, Physiology; Training Program in Translational Cardiovascular Science

Cardiac myosin missense mutations cause dilated cardiomyopathy in mouse models and depress molecular motor function Joachim P. Schmitt, Edward P. Debold, Ferhaan Ahmad, Amy Armstrong, Andrea Frederico, David A. Conner, Ulrike Mende, Martin J. Lohse, David Warshaw, Christine E. Seidman, and J.G. Seidman PNAS 2006;103;14525-14530; originally published online Sep 18, 2006.

Dec. 14, 2006
Carl W. Tong, MD, Ph.D., Medicine, Postdoctoral Trainee, Training Program in Translational Cardiovascular Science

Cardiac myosin binding protein c phosphorylation is cardioprotective Sakthivel Sadayappan, Hanna Osinska, Raisa Klevitsky, John N. Lorenz, Michelle Sargent, Jeffrey D. Molkentin, Christine E. Seidman, Jonathan G. Seidman, and Jeffrey Robbins PNAS 2006;103;16918-16923

Myosin binding protein C is differentially phosphorylated upon myocardial stunning in canine and rat hearts­Evidence for novel phosphorylation sites Chao Yuan, Yurong Guo, Rajashree Ravi, Karin Przyklenk, Nicole Shilkofski, Roberto Diez, Robert N. Cole and Anne M. Murphy. Proteomics 2006, 6, 4176–418

Spring 2007

Jan. 11, 2007
Ravi C. Balijepalli, Ph.D., Assistant Scientist, Medicine (Cardiovascular)

Improvement of Peripheral Endothelial Dysfunction by Protein Tyrosine Phosphatase Inhibitors in Heart Failure Magali Vercauteren, Elise Remy, Corinne Devaux, Brigitte Dautreaux, Jean-Paul Henry, Fabrice Bauer, Paul Mulder, Rob Hooft van Huijsduijnen, Agnès Bombrun, Christian Thuillez and Vincent Richard Circulation  2006;114:2498-2507

Feb. 8, 2007
Sandy Dunning Graduate Student, Physiology; Trainee, Training Program in Translational Cardiovascular Science

Fibrosis, not cell size, delineates b-myosin heavy chain reexpression during cardiac hypertrophy and normal aging in vivo  Kumar Pandya, Hyung-Suk Kim, Oliver Smithies PNAS November 7, 2006 vol. 103, no 45 pp 16864-16869

Mar. 8, 2007
Blue-leaf Cordes, MD, Ph.D, Postdoc, Medicine (Hematology); Trainee, Training Program in Translational Cardiovascular Science

Thrombospondin-2 Is Essential for Myocardial Matrix Integrity: Increased Expression Identifies Failure-Prone Cardiac Hypertrophy  Blanche Schroen, Stephane Heymans, Umesh Sharma, W. Matthijs Blankesteijn, Saraswati Pokharel, Jack P.M. Cleutjens, J. Gordon Porter, Chris T.A. Evelo, Rudy Duisters, Rick E.W. van Leeuwen, Ben J.A. Janssen, Jacques J.M. Debets, Jos F.M. Smits, Mat J.A.P. Daemen, Harry J.G.M. Crijns, Paul Bornstein and Yigal M. Pinto Circ. Res. 2004;95;515-522; originally published online Jul 29, 2004.

Apr. 12, 2007
Nathan Evans Graduate Student, Physiology; Trainee, Training Program in Translational Cardiovascular Science

Factor XIIIA Transglutaminase Crosslinks AT₁ Receptor Dimers of Monocytes at the Onset of Atherosclerosis, Said AbdAlla, Heinz Lother, Andreas Langer, Yasser el Faramawy, and Ursula Quitterer Cell, Vol. 119, 343–354, October 29, 2004.

May 10, 2007
Matt Locher, Graduate Student, Physiology.

Impact of Beta-Myosin Heavy Chain Expression on Cardiac Function During Stress, Maike Krenz, MD, Jeffrey Robbins, Ph.D.  Journal of the American College of Cardiology Vol. 44, No. 12, 2004 :2390–7

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