Arrhythmias/Ion Channels Journal Club Schedule
(2008-2009)

Fourth Thursdays, 11 AM - 12:30 PM
Room 116 Service Memorial Institute
1300 University Avenue
Jonathan C. Makielski, MD, Professor, Cardiovascular Medicine, Chair
Contact info@cvrc.wisc.edu or 263-2266 for further information

Fall 2008

Sep. 25, 2008
Ravi C. Balijepalli, Ph.D., Assistant Scientist, Cellular and Molecular Arrhythmia Research Program

Location, Location, Location: Why Neighborhood Matters to L-Type Ca2+ Channels

Oct. 23, 2008
Lee L. Eckhardt, MD, Assistant Professor, Cardiovascular Medicine

Arrhythmogenic mechanisms in a mouse model of catecholaminergic polymorphic ventricular tachycardia. Cerrone,M., Noujaim,S.F., Tolkacheva,E.G., Talkachou,A., O'Connell,R., Berenfeld,O., Anumonwo,J., Pandit,S.V., Vikstrom,K., Napolitano,C. et al. Nov 2007. Circ.Res. 101:1039-1048.

Nov. 20, 2008 (one week early due to holiday)
Deborah Capes, Graduate Student, Molecular and Cellular Pharmacology Trainee, Training Program in Translational Cardiovascular Science

Molecular and Clinical Characterization of a Novel SCN5A Mutation Associated With Atrioventricular Block and Dilated Cardiomyopathy Junbo Ge, Aijun Sun, Vesa Paajanen, Shijun Wang, Chunxi Su, Zhiyin Yang, Ying Li, Shaochun Wang, Jianguo Jia, Keqiang Wang, Yunzeng Zou, Lizhi Gao, Kun Wang and Zheng Fan Circ Arrhythmia Electrophysiol 2008;1;83-92

Spring 2009

Jan. 22, 2009
Baron Chanda, Ph.D., Assistant Professor, Physiology

Deconstructing voltage sensor function and pharmacology in sodium channels, Frank Bosmans, Marie-France Martin-Eauclaire & Kenton J. Swartz Nature Vol 456 13 November 2008; 202-209

Feb. 26, 2009
Eric Lin, Graduate Student, Physiology

Biophysical Characterization of the Short QT Mutation hERG-N588K Reveals a Mixed Gain-and Loss-of-Function Morten Grunnet, Thomas Goldin Diness, Rie Schultz Hansen and Søren-Peter Olesen Cell Physiol Biochem 2008;22:611-624

Mar. 26, 2009
Elon Roti Roti, Graduate Student, Cellular and Molecular Biology Trainee, Training Program in Translational Cardiovascular Science

LQT1-associated Mutations Increase KCNQ1 Proteasomal Degradation Independently of Derlin-1*  David Peroz, Shehrazade Dahimene, Isabelle Baro, Gildas Loussouarn, and Jean Merot.  Journal of Biological Chemistry, VOL. 284, NO. 8, pp. 5250–5256, February 20, 2009

Apr. 23, 2009
Gail A. Robertson, Ph.D., Professor, Physiology

Synchronization of chaotic early afterdepolarizations in the genesis of cardiac arrhythmias Daisuke Sato, Lai-Hua Xie, Ali A. Sovari, Diana X. Tran, Norishige Morita, Fagen Xie, Hrayr Karagueuzian, Alan Garfinkel, James N. Weiss, and Zhilin Qu PNAS, March 3, 2009, vol. 106, no. 9; 2983–2988.

May 28, 2009
Bikash Pattnaik, Ph.D., Associate Scientist, Pediatrics.

Dynamic partnership between KCNQ1 and KCNE1 and influence on cardiac IKS current amplitude by KCNE2 Min Jiang, Xulin Xu, Yuhong Wang, Futoshi Toyoda, Xian-Sheng Liu, Mei Zhang, Richard B. Robinson, and Gea-Ny Tseng Journal of Biological Chemistry April 16, 2009 epublish manuscript M808262200

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