
Ion Channels/Arrhythmia Journal Club Presentations
Fourth Thursdays, 11 AM - 12:30 PM
(Unless otherwise noted)
Room 116 Service Memorial Institute
1300 University Avenue
Jonathan C. Makielski, MD, Professor, Medicine, Chair
Contact
info@cvrc.wisc.edu for further information
2003-2004
Oct. 23, 2003, Gail Robertson, Ph.D., Associate Professor, Physiology.
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William N. Zagotta, Nelson B. Olivier, Kevin D. Black, Edgar C. Young, Rich Olson & Eric Gouaux ,
Structural basis for modulation and agonist specificity of HCN
pacemaker channels. Nature 425: 200-205, 11 Sept. 2003.
Nov. 20, 2003 (one week early due to holiday).
Roberto Coronado, Ph.D., Professor, Physiology.
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Jiang, Ruta, Chen, Lee and MacKinnon,
“Voltage sensors are out not in”
The principle of gating charge movement in a voltage-dependent K+ channel,
Nature 423: 42-48, 2003.
Dec. 18, 2003 (one week early due to holiday).
Bin Ye, Ph.D., Research Associate, Medicine (Cardiovascular).
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Stieber J, Herrmann S, Feil S, Loster J, Feil R, Biel M, Hofmann F, Ludwig A,
The hyperpolarization-activated channel HCN4 is required for the
generation of pacemaker action potentials in the embryonic heart.
Proc Natl Acad Sci U S A. 2003 Dec 9;100(25):15235-15240.
Jan. 22, 2004.
Hector H. Valdivia, MD, Ph.D., Associate Professor, Physiology.
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Arrhythmias and Sudden Cardiac Death:
Intracellular Calcium Channels Also Count.
George C.H., et al,
Ryanodine Receptor Mutations Associated With
Stress-Induced Ventricular Tachycardia Mediate Increased Calcium Release
in Stimulated Cardiomyocytes.
Circ Res. 2003;93:531-540
Viatchenko-Karpinski S, et al,
Abnormal Calcium Signaling and Sudden
Cardiac Death Associated With Mutation of Calsequestrin.
Circ. Res. 2004.
Feb. 26, 2004.
Blake Anson, Ph.D. Assistant Scientist, Medicine (Cardiovascular)
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Kupershmidt S, Yang IC, Hayashi K, Wei J, Chanthaphaychith S, Petersen
CI, Johns DC, George AL Jr, Roden DM, Balser JR,
“The IKr drug response is modulated by KCR1 in transfected cardiac and
noncardiac cell lines"
FASEB J. 2003
Dec;17(15):2263-5. Epub 2003 Oct 02.
Mar. 25, 2004.
Brian P. Delisle, Ph.D., Research Associate, Medicine (Cardiovascular)
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Christopher A. Ahern and Richard Horn,
"Specificity of Charge-carrying Residues in the Voltage Sensor of Potassium Channels"
J. Gen. Physiol. 2004 123: 205-216.
Apr. 22, 2004.
Pallavi Phartiyal, Graduate Student, Physiology
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Krumerman A, Gao X, Bian JS, Melman YF, Kagan A, McDonald TV
"An LQT Mutant minK Alters KvLQT1 Trafficking"
Am J Physiol Cell Physiol. 2004 Feb 4 [Epub ahead of print]
[PDF].
May 27, 2004.
Elon Roti Roti, Graduate Student, Cellular and Molecular Biology and Trainee, Training Program in Translational Cardiovascular Science
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"Prolonged repolarization and triggered activity induced by adenoviral expression of HERG N629D in cardiomyocytes derived from stem cells"
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